HPA axis - Thyroid, Adrenal, Pituitary and Hypothalmus glands Treatments

Important Note
If tests show that you suffer from any of these abnormalities / dysfunctions, you can view the treatment options available and discuss them with your own medical doctor or consultant. These treatments can only be undertaken with the permission and supervision of your own medical doctor

 

Thyroid gland Treatments

  • An Endocrinologist can advise on appropriate treatments
  • Subclinical Thyroid gland disorders occur in ME and Fibromyalgia.
  • Reverse T3 levels, this is the most important biomarker in ME. Reduce levels of Reverse T3 through medical treatment, this may take several months, and up to year. Also increase levels of T3 through medical treatment, this may take several months, and up to year. These treatments must be carefully planned / designed, supervised and monitored by a medical doctor.
  • TRH test - if abnormal, then treat medically. If values are near the borderline, then treat for the disorder as subclinical Thyroid gland disorders occur in ME and Fibromyalgia.
  • TPO - if positive, T4 & T3 dosage will need to be increased. (Dr. Austin Darrah)
  • T4 - free and bound. If abnormal, then treat medically.
  • T3 - free (often low even if T4 is normal in ME due to the sick thyroid syndrome). If abnormal, then treat medically.
  • Defects, abnormalities in the conversion of T4 to T3. If abnormal, then treat medically
  • Level of thyroid hormone bound to thyroid binding globulin. If abnormal, then treat medically.
  • TSH - if abnormal, then treat medically. If values are near the borderline, then treat for the disorder as subclinical Thyroid gland disorders occur in ME and Fibromyalgia.
  • Dr. Sarah Myhill, Wales, UK (CFS expert) recommends the following: "I routinely check T4 in all my CFS patients. If the level falls in the lowest 20% of the so called "normal" range then I would treat with thyroxine. I often find GPs complaining that the best test of thyroid failure is a TSH - thyroid stimulating hormone. However this is often normal even with a low T4. I suspect this reflects the hypothalamic-pituitary-adrenal hypofunction in CFS."
    Dr. Sarah Myhill www.drmyhill.co.uk
  • Thyroid Function (Dr. Kenny De Meirleir) Thyroid dysfunction is present despite normal blood tests. There is both poor conversion of T4 to T3 and peripheral resistance to T3. Peripheral resistance is present in all dys-immune diseases. An immune activation protein has a 98% homology with the T3 receptor, binding to it and competing with T3. Kenny recommends treating with pure T3. He recommends starting low and titrating up. Patients appear to have destruction of T3 receptors over time - and after a long duration of CFS (e.g., 20 to 25 years) often do not lose weight on extremely low calorie diets (e.g., 800 calories) due to thyroid insensitivity
  • Oxytocin has multiple effects on the human body and hormones. Check Oxytocin levels, if low, then take medical drugs and supplements to increase and normalise levels.
  • Check phenylalanine and tyrosine levels. Over 80% of ME patients are low in these amino acids according to Dr. Edward Conley, and this adversely affects thyroid function. If levels are too low then use supplements to normalise them. Do not overdose. (Dr. Edward Conley)
  • Armour Thyroid supplement
  • Important Minerals
    Take adeqaute iodine, zinc and selenium supplements to normalise thyroid function.
  • Herbs
    Siberian Ginseng, Rhodiola, Kelp and Sea weeds, Iodine, Coconut oil, Ashwagandha, Agnus Castus, Poke root can help normalise thyroid gland functions.
  • If scans reveal structural damage to Thyroid gland, then treat medically.
  • Mitochondria Repair
    Cell wall deficient pathogens and co-infections such as Mycoplasmas, Lyme, Bartonella, Ehirlichia, Babesia, Brucella, Chlamydia, Enteroviruses, Herpes viruses 1-8 which have been found in patients inflict substantial damage to the mitochondria membrane and cell membrane and joints, nerves, blood vessels and glands over time. Mitochondria membrane repair and cell membrane repair
  • Homeopathy
    • The Homeopathic remedy apo-STRUM spag. drops helps normalise thyroid functions.
  • Get 6 - 7 hours of daylight or sunlight during the day, every day. In Winter, the use of light boxes will be necessary. This light is important for hormonal functions and will help normalise all of your hormones over time.
  • Additional Measures
    • Lifestyle - Bed by 10pm. Light exercise gradually. Reduce stress. 9-10 hours deep sleep every night.
    • Energy Restoration - mitochondrial enhancement. Thyroid normalisation. DHEA 25-75 ug. CO-Q10 30-300mg. Avoidance of anti-bacterial drugs. Vitamins B and C.
    • General Nutrition - Water, Nacl. Low Carbohydrate, Low sugar. Regular meals, no hypoglycaemia.
    • General Endocrinology - Males normalisation. Females PMT Progesterone ND
  • Re-designating old medical drugs for CFS Treatment
    CFIDS Association of America has got Biovista ( http://biovista.com ) in the USA to engage in research and data mining of thousands of medical drugs (including some which are currently out of use) and find matches between them and the symptoms, abnormalities and dysfunctions found in ME. They are compiling a list of these medical drugs. Safety guidelines, side effects, clinical reports and general efficacy and other factors will also be taken into account for each medical drug
  • Stress Reduction
    In addition to getting medical treatment for immune system, krebs cycle and methylation cycle dysfunctions, infections and other biological abnormalities and dysfunctions one should also get Stress Reduction treatment as all physical illnesses including Cancer, AIDS, ME, Multiple Sclerosis, Fibromyalgia, autoimmune illness, Cardiac related illnesses, advanced Diabetes, etc. causes great stress for patients. Click here for Stress Reduction treatment

Adrenal gland Treatments

  • An Endocrinologist can advise on appropriate treatments
  • Subclinical Adrenal gland disorders occur in ME and Fibromyalgia.
  • If cortisol level abnormal, then treat medically. If values are near the borderline, then treat for the disorder as subclinical Adrenal gland disorders occur in ME and Fibromyalgia.
  • If DHEA level abnormal, then treat medically. If values are near the borderline, then treat for the disorder as subclinical Adrenal gland disorders occur in ME and Fibromyalgia.
  • If estrogen, progesterone, testosterone levels abnormal, then treat medically. If values are near the borderline, then treat for the disorder as subclinical Adrenal gland disorders occur in ME and Fibromyalgia.
  • Oxytocin has multiple effects on the human body and hormones. Check Oxytocin levels, if low, then take medical drugs and supplements to increase and normalise levels.
  • If scans reveal structural damage to Adrenal gland, then treat medically.
  • Adrenal Cortical Extract or Adrenal extract (Dr. Edward Conley)
  • The following supplements assist the adrenals recover
    • Dessicated adrenal twice a day. Or Adrenal Cortical Extract or Adrenal extract
    • Vitamin C
    • B-Complex.
    • Vitamin B12
    • Trace minerals
    • Amino acids
    • Phosphorylated serine
    • a hypoglycaemic diet . (Dr. Edward Conley)
  • The folowing herbs can improve adrenal gland recovery
    • Borage (the best)
    • Siberian Ginseng
    • Rhodiola
    • Licorice
    • Sarsaparilla
    • Gotu Kola
    • Wild Yam
    • Ashwagandha
    • Kelp, seaweeds, Iodine
  • Mitochondria Repair
    Cell wall deficient pathogens and co-infections such as Mycoplasmas, Lyme, Bartonella, Ehirlichia, Babesia, Brucella, Chlamydia, Enteroviruses, Herpes viruses 1-8 which have been found in patients inflict substantial damage to the mitochondria membrane and cell membrane and joints, nerves, blood vessels and glands over time. Mitochondria membrane repair and cell membrane repair
  • Homeopathy
    • The Homeopathic remedy SUPREN spag. drops helps normalise adrenal functions.
  • Additional Measures
    • Lifestyle - Bed by 10pm. Light exercise gradually. Reduce stress. 9-10 hours deep sleep every night.
    • Energy Restoration - mitochondrial enhancement. Thyroid normalisation. DHEA 25-75 ug. CO-Q10 30-300mg. Avoidance of anti-bacterial drugs. Vitamins B and C.
    • General Nutrition - Water, Nacl. Low Carbohydrate, Low sugar. Regular meals, no hypoglycaemia.
    • General Endocrinology - Males normalisation. Females PMT Progesterone ND
  • Re-designating old medical drugs for CFS Treatment
    CFIDS Association of America has got Biovista ( http://biovista.com ) in the USA to engage in research and data mining of thousands of medical drugs (including some which are currently out of use) and find matches between them and the symptoms, abnormalities and dysfunctions found in ME. They are compiling a list of these medical drugs. Safety guidelines, side effects, clinical reports and general efficacy and other factors will also be taken into account for each medical drug
  • Stress Reduction
    In addition to getting medical treatment for immune system, krebs cycle and methylation cycle dysfunctions, infections and other biological abnormalities and dysfunctions one should also get Stress Reduction treatment as all physical illnesses including Cancer, AIDS, ME, Multiple Sclerosis, Fibromyalgia, autoimmune illness, Cardiac related illnesses, advanced Diabetes, etc. causes great stress for patients. Click here for Stress Reduction treatment
Female hormones
  • An Endocrinologist can advise on appropriate treatments
  • Midcycle, FSH, LH, Oestradiol, Progesterone. If abnormal then treat medically. If values are near the borderline, then treat for the disorder as subclinical female hormone disorders occur in ME and Fibromyalgia.
  • Oxytocin has multiple effects on the human body and hormones. Check Oxytocin levels, if low, then take medical drugs and supplements to increase and normalise levels.
  • Herbs
    Dong Quai, Ginseng can help normalise female hormones
  • Mitochondria Repair
    Cell wall deficient pathogens and co-infections such as Mycoplasmas, Lyme, Bartonella, Ehirlichia, Babesia, Brucella, Chlamydia, Enteroviruses, Herpes viruses 1-8 which have been found in patients inflict substantial damage to the mitochondria membrane and cell membrane and joints, nerves, blood vessels and glands over time. Mitochondria membrane repair and cell membrane repair
  • Additional Measures
    • Lifestyle - Bed by 10pm. Light exercise gradually. Reduce stress. 9-10 hours deep sleep every night.
    • Energy Restoration - mitochondrial enhancement. Thyroid normalisation. DHEA 25-75 ug. CO-Q10 30-300mg. Avoidance of anti-bacterial drugs. Vitamins B and C.
    • General Nutrition - Water, Nacl. Low Carbohydrate, Low sugar. Regular meals, no hypoglycaemia.
    • General Endocrinology - Males normalisation. Females PMT Progesterone ND
  • Re-designating old medical drugs for CFS Treatment
    CFIDS Association of America has got Biovista ( http://biovista.com ) in the USA to engage in research and data mining of thousands of medical drugs (including some which are currently out of use) and find matches between them and the symptoms, abnormalities and dysfunctions found in ME. They are compiling a list of these medical drugs. Safety guidelines, side effects, clinical reports and general efficacy and other factors will also be taken into account for each medical drug
  • Stress Reduction
    In addition to getting medical treatment for immune system, krebs cycle and methylation cycle dysfunctions, infections and other biological abnormalities and dysfunctions one should also get Stress Reduction treatment as all physical illnesses including Cancer, AIDS, ME, Multiple Sclerosis, Fibromyalgia, autoimmune illness, Cardiac related illnesses, advanced Diabetes, etc. causes great stress for patients. Click here for Stress Reduction treatment

 

Male hormones

  • An Endocrinologist can advise on appropriate treatments
  • Testosterone (random). If abnormal then treat medically. If values are near the borderline, then treat for the disorder as subclinical male hormone disorders occur in ME and Fibromyalgia.
  • PSA (to eliminate prostrate hypertrophy / cancer). If abnormal then treat medically
  • Oxytocin has multiple effects on the human body and hormones. Check Oxytocin levels, if low, then take medical drugs and supplements to increase and normalise levels.
  • Herbs
    Ginseng, Sarsaparilla, and Licorice can help normalise male hormones
  • Mitochondria Repair
    Cell wall deficient pathogens and co-infections such as Mycoplasmas, Lyme, Bartonella, Ehirlichia, Babesia, Brucella, Chlamydia, Enteroviruses, Herpes viruses 1-8 which have been found in patients inflict substantial damage to the mitochondria membrane and cell membrane and joints, nerves, blood vessels and glands over time. Mitochondria membrane repair and cell membrane repair
  • Additional Measures
    • Lifestyle - Bed by 10pm. Light exercise gradually. Reduce stress. 9-10 hours deep sleep every night.
    • Energy Restoration - mitochondrial enhancement. Thyroid normalisation. DHEA 25-75 ug. CO-Q10 30-300mg. Avoidance of anti-bacterial drugs. Vitamins B and C.
    • General Nutrition - Water, Nacl. Low Carbohydrate, Low sugar. Regular meals, no hypoglycaemia.
    • General Endocrinology - Males normalisation. Females PMT Progesterone ND
  • Re-designating old medical drugs for CFS Treatment
    CFIDS Association of America has got Biovista ( http://biovista.com ) in the USA to engage in research and data mining of thousands of medical drugs (including some which are currently out of use) and find matches between them and the symptoms, abnormalities and dysfunctions found in ME. They are compiling a list of these medical drugs. Safety guidelines, side effects, clinical reports and general efficacy and other factors will also be taken into account for each medical drug
  • Stress Reduction
    In addition to getting medical treatment for immune system, krebs cycle and methylation cycle dysfunctions, infections and other biological abnormalities and dysfunctions one should also get Stress Reduction treatment as all physical illnesses including Cancer, AIDS, ME, Multiple Sclerosis, Fibromyalgia, autoimmune illness, Cardiac related illnesses, advanced Diabetes, etc. causes great stress for patients. Click here for Stress Reduction treatment

Hypothalmus gland Treatments

  • An Endocrinologist can advise on appropriate treatments
  • If Deficiency of Hypothalmic hormones, then treat medically. If values are near the borderline, then treat for the disorder as subclinical Hypothalmus gland disorders occur in ME and Fibromyalgia. ADH and Oxytocin are usually low in ME. Some nasal sprays contain ADH and Oxytocin.
  • If scans reveal structural damage to Hypothalmus gland, then treat medically.
  • Siberain Ginseng and Rhodiola can help normalise Hypothalmus functions.
  • Mitochondria Repair
    Cell wall deficient pathogens and co-infections such as Mycoplasmas, Lyme, Bartonella, Ehirlichia, Babesia, Brucella, Chlamydia, Enteroviruses, Herpes viruses 1-8 which have been found in patients inflict substantial damage to the mitochondria membrane and cell membrane and joints, nerves, blood vessels and glands over time. Mitochondria membrane repair and cell membrane repair
  • Additional Measures
    • Lifestyle - Bed by 10pm. Light exercise gradually. Reduce stress. 9-10 hours deep sleep every night.
    • Energy Restoration - mitochondrial enhancement. Thyroid normalisation. DHEA 25-75 ug. CO-Q10 30-300mg. Avoidance of anti-bacterial drugs. Vitamins B and C.
    • General Nutrition - Water, Nacl. Low Carbohydrate, Low sugar. Regular meals, no hypoglycaemia.
    • General Endocrinology - Males normalisation. Females PMT Progesterone ND
  • Re-designating old medical drugs for CFS Treatment
    CFIDS Association of America has got Biovista ( http://biovista.com ) in the USA to engage in research and data mining of thousands of medical drugs (including some which are currently out of use) and find matches between them and the symptoms, abnormalities and dysfunctions found in ME. They are compiling a list of these medical drugs. Safety guidelines, side effects, clinical reports and general efficacy and other factors will also be taken into account for each medical drug
  • Stress Reduction
    In addition to getting medical treatment for immune system, krebs cycle and methylation cycle dysfunctions, infections and other biological abnormalities and dysfunctions one should also get Stress Reduction treatment as all physical illnesses including Cancer, AIDS, ME, Multiple Sclerosis, Fibromyalgia, autoimmune illness, Cardiac related illnesses, advanced Diabetes, etc. causes great stress for patients. Click here for Stress Reduction treatment

 

Pituitary gland Treatments

  • An Endocrinologist can advise on appropriate treatments
  • If Deficiency of Pituitary hormones, then treat medically. If values are near the borderline, then treat for the disorder as subclinical Pituitary gland disorders occur in ME and Fibromyalgia.
  • Growth Hormone is usually very low in ME and Fibromyalgia. Injections of growth hormone may help normalise levels. Combining Whey protein, Colostrum and Vitamin C can also improve growth hormone levels.
    - Moorkens G , Wynants H , Abs R . Effect of growth hormone treatment in patients with chronic fatigue syndrome: a preliminary study. Growth Horm IGF Res. 1998 Apr;8 Suppl B:131-3. PMID: 10990148
  • Oxytocin has multiple effects on the human body and hormones. Check Oxytocin levels, if low, then take medical drugs and supplements to increase and normalise levels.
  • If scans reveal structural damage to Pituitary gland, then treat medically.
  • Herbs
    Siberain Ginseng, Rhodiola, Wild yam, Agnus Castus, Walnut, Gotu Kola, Sarsaparilla, Prickly ash, Kelp, and Ginkgo can help normalise Pituitary functions.
  • Mitochondria Repair
    Cell wall deficient pathogens and co-infections such as Mycoplasmas, Lyme, Bartonella, Ehirlichia, Babesia, Brucella, Chlamydia, Enteroviruses, Herpes viruses 1-8 which have been found in patients inflict substantial damage to the mitochondria membrane and cell membrane and joints, nerves, blood vessels and glands over time. Mitochondria membrane repair and cell membrane repair
  • Additional Measures
    • Lifestyle - Bed by 10pm. Light exercise gradually. Reduce stress. 9-10 hours deep sleep every night.
    • Energy Restoration - mitochondrial enhancement. Thyroid normalisation. DHEA 25-75 ug. CO-Q10 30-300mg. Avoidance of anti-bacterial drugs. Vitamins B and C.
    • General Nutrition - Water, Nacl. Low Carbohydrate, Low sugar. Regular meals, no hypoglycaemia.
    • General Endocrinology - Males normalisation. Females PMT Progesterone ND
  • Re-designating old medical drugs for CFS Treatment
    CFIDS Association of America has got Biovista ( http://biovista.com ) in the USA to engage in research and data mining of thousands of medical drugs (including some which are currently out of use) and find matches between them and the symptoms, abnormalities and dysfunctions found in ME. They are compiling a list of these medical drugs. Safety guidelines, side effects, clinical reports and general efficacy and other factors will also be taken into account for each medical drug
  • Stress Reduction
    In addition to getting medical treatment for immune system, krebs cycle and methylation cycle dysfunctions, infections and other biological abnormalities and dysfunctions one should also get Stress Reduction treatment as all physical illnesses including Cancer, AIDS, ME, Multiple Sclerosis, Fibromyalgia, autoimmune illness, Cardiac related illnesses, advanced Diabetes, etc. causes great stress for patients. Click here for Stress Reduction treatment

 

Pineal gland Treatments

  • An Endocrinologist can advise on appropriate treatments
  • If Deficiency of Melatonin, then treat medically and through supplements.
    - van Heukelom RO , Prins JB , Smits MG , Bleijenberg G . Influence of melatonin on fatigue severity in patients with chronic fatigue syndrome and late melatonin secretion. Eur J Neurol. 2006 Jan;13(1):55-60. PMID: 16420393
  • Herbs
    Gotu Kola, Horsetail, Guaiacum, Ginseng, Kelp, Safflower
  • Vitamins and Minerals
    B vitamins, Iodine, Magnesium
  • Sleep and Darkness
    1 hour of complete darkness before sleep every night. This improves Pineal gland functions.
    During the day time get plenty of sunlight and use a light box during the Autumn and Winter.
  • Re-designating old medical drugs for CFS Treatment
    CFIDS Association of America has got Biovista ( http://biovista.com ) in the USA to engage in research and data mining of thousands of medical drugs (including some which are currently out of use) and find matches between them and the symptoms, abnormalities and dysfunctions found in ME. They are compiling a list of these medical drugs. Safety guidelines, side effects, clinical reports and general efficacy and other factors will also be taken into account for each medical drug
  • Stress Reduction
    In addition to getting medical treatment for immune system, krebs cycle and methylation cycle dysfunctions, infections and other biological abnormalities and dysfunctions one should also get Stress Reduction treatment as all physical illnesses including Cancer, AIDS, ME, Multiple Sclerosis, Fibromyalgia, autoimmune illness, Cardiac related illnesses, advanced Diabetes, etc. causes great stress for patients. Click here for Stress Reduction treatment

 

Endocrine Other

  • An Endocrinologist can advise on appropriate treatments
  • Deficiency of Aldosterone then treat medically.

  • If Low Albumin levels then treat medically.
  • Get MRI / CAT scans for thorough Pituitary gland, Thyroid gland, Adrenal gland and Hypothlamus gland analysis  -  both structural and functional analysis. If abnormal, then treat medically.
  • Additional Measures
    • Lifestyle - Bed by 10pm. Light exercise gradually. Reduce stress. 9-10 hours deep sleep every night.
    • Energy Restoration - mitochondrial enhancement. Thyroid normalisation. DHEA 25-75 ug. CO-Q10 30-300mg. Avoidance of anti-bacterial drugs. Vitamins B and C.
    • General Nutrition - Water, Nacl. Low Carbohydrate, Low sugar. Regular meals, no hypoglycaemia.
    • General Endocrinology - Males normalisation. Females PMT Progesterone ND
  • Re-designating old medical drugs for CFS Treatment
    CFIDS Association of America has got Biovista ( http://biovista.com ) in the USA to engage in research and data mining of thousands of medical drugs (including some which are currently out of use) and find matches between them and the symptoms, abnormalities and dysfunctions found in ME. They are compiling a list of these medical drugs. Safety guidelines, side effects, clinical reports and general efficacy and other factors will also be taken into account for each medical drug
  • Stress Reduction
    In addition to getting medical treatment for immune system, krebs cycle and methylation cycle dysfunctions, infections and other biological abnormalities and dysfunctions one should also get Stress Reduction treatment as all physical illnesses including Cancer, AIDS, ME, Multiple Sclerosis, Fibromyalgia, autoimmune illness, Cardiac related illnesses, advanced Diabetes, etc. causes great stress for patients. Click here for Stress Reduction treatment

Research articles & Clinical Findings
-
some ME clinics use this. See listing of clinics in Diagnosis and Treatments section

Return to Treatment Listing